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Cardiovascular

Dental Management of Patients with Previous infective endocarditis

Antibiotic prophylaxis indicated (previous IE)

Previous infective endocarditis is a high-risk cardiac condition. Prophylaxis is recommended for procedures involving gingival/periapical manipulation or mucosal perforation.

Emergency vs routine management

If EMERGENCY — what to do

  • • Antibiotic prophylaxis 30–60 min before: amoxicillin 2 g orally (child 50 mg/kg). Penicillin-allergic: azithromycin/clarithromycin 500 mg or doxycycline 100 mg — clindamycin is no longer recommended. If missed, it can be given up to 2 h after the procedure.Ref: Wilson WR et al. Prevention of Viridans Group Streptococcal Infective Endocarditis — AHA Scientific Statement. Circulation 2021;143:e963–e978
  • • Treat any dental infection immediately — it is a potential source of recurrent endocarditis; refer if fever or malaise.Ref: Wilson WR et al. Prevention of Viridans Group Streptococcal Infective Endocarditis — AHA Scientific Statement. Circulation 2021;143:e963–e978

If ROUTINE — what to do

  • • Prophylaxis is required for every procedure involving gingival manipulation, the periapical region or perforation of the oral mucosa — not for routine LA injections through non-infected tissue or radiographs.Ref: Wilson WR et al. Prevention of Viridans Group Streptococcal Infective Endocarditis — AHA Scientific Statement. Circulation 2021;143:e963–e978
  • • Highest-risk group: intensive prevention and close recall.Ref: Wilson WR et al. Prevention of Viridans Group Streptococcal Infective Endocarditis — AHA Scientific Statement. Circulation 2021;143:e963–e978

Clinical precautions

  • • Amoxicillin 2 g PO 30–60 min before (adult)
  • • Penicillin-allergic alternatives per AHA 2021

At a glance by procedure

Initial assessment before lab results or timing details are entered.

ProcedureInitial assessment
Examination / radiographsROUTINE

No prophylaxis needed for this procedure

Supragingival scaling / polishMODIFY / CAUTION

Antibiotic prophylaxis indicated (previous IE)

Deep scaling / subgingival RSD (subgingival calculus)MODIFY / CAUTION

Antibiotic prophylaxis indicated (previous IE)

Root canal treatmentROUTINE

No prophylaxis needed for this procedure

Simple extraction (1–3 teeth)MODIFY / CAUTION

Antibiotic prophylaxis indicated (previous IE)

Surgical / bony extractionMODIFY / CAUTION

Antibiotic prophylaxis indicated (previous IE)

Implant placementMODIFY / CAUTION

Antibiotic prophylaxis indicated (previous IE)

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References

  1. AHA 2021 — Prevention of Infective Endocarditis
  2. Wilson WR et al. Prevention of Viridans Group Streptococcal Infective Endocarditis — AHA Scientific Statement. Circulation 2021;143:e963–e978

Related guides

This guide supports — and does not replace — professional clinical judgment. Always consider the individual patient and consult the treating physician when indicated.